EVALUATION OF MALARIA TREATMENT AMONG PEOPLE LIVING WITH HIV

Abstract

An evaluation study was conducted on treatment of malaria among people living with HIV, reported cases obtained from United Nation Agency for International Development and Studies (UNAIDS) and World Health Organization (WHO) were used in the research work. It was observed that Malaria in people with HIV has recorded more than 4 million deaths yearly. The treatment of malaria for people living with HIV infection showed a synergistical interaction with each other. Patients with HIV infection are at high risk of an increase in the severity and burdens malaria infection which in turn facilitates the rate of malaria transmission. Malaria increases blood viral burden by different mechanisms. Therefore, high concentrations of HIV-1 RNA in the blood are predictive of disease progression, and correlate with the risk of blood-borne, vertical, and sexual transmission of the HIV virus. Furthermore, Malaria infection is also associated with strong CD4+ cell activation and up-regulation of pro inflammatory cytokines and it provides an ideal microenvironment for the spread of the virus among the CD4+ cells and for rapid HIV-1 replication. Therefore, this article aims to review information about HIV/malaria interactions, the effect of malaria on HIV transmission, treatment and the implications related to prevention of the disease.